Detection of Adduct on Tyrosine 411 of Albumin in Humans Poisoned by Dichlorvos
نویسندگان
چکیده
منابع مشابه
Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos.
Studies in mice and guinea pigs have shown that albumin is a new biomarker of organophosphorus toxicant (OP) and nerve agent exposure. Our goal was to determine whether OP-labeled albumin could be detected in the blood of humans exposed to OP. Blood from four OP-exposed patients was prepared for mass spectrometry analysis by digesting 0.010 ml of serum with pepsin and purifying the labeled albu...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2010
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfq117